• dandelion (she/her)@lemmy.blahaj.zone
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      1 day ago

      For transfeminine folks, too much estrogen can be a bad thing. This is because estrogen and testosterone can be converted between each other in the body. Too much estrogen can lead to more testosterone.

      hey there, I was hoping you could edit your comment to remove this misinformation, only testostetrone can be converted to estrogen through aromatization (basically this enzyme aromatase converts the excess T into E). Excess estrogen does not convert to testosterone in the body.

      here’s a chart showing the sex steroid pathways: https://en.wikipedia.org/wiki/Sex_hormone#/media/File:Steroidogenesis.svg

      Notice testosterone can convert to DHT (Dihydrotestosterone, which causes baldness), and estradiol (estrogen), but there is no pathway from estradiol back to testosterone.

      • AnarchistArtificer@slrpnk.net
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        13 hours ago

        Changed! Really appreciate you commenting to point this out. To get a bit meta on you, I really love that you corrected me, because that’s a perfect microcosm of the iterative knowledge building that leads to robust networks of community learning.

        • dandelion (she/her)@lemmy.blahaj.zone
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          10 hours ago

          thanks for being so receptive to correction!

          and yeah, definitely love when a group is able to help fill in gaps - I owe so much to internet communities (Wikipedia being an extreme version of this dynamic)

    • amino@lemmy.blahaj.zone
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      1 day ago

      this is bullshit, estrogen doesn’t convert into testosterone. people often make this assumption because it’s true for the T to E pathway

      • AnarchistArtificer@slrpnk.net
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        13 hours ago

        Yeah, that was an error and I corrected it. Apologies for inadvertently spreading misinformation, but thank you for calling me out on it, because that’s an important part of how we build communities of learning

      • TotallynotJessica@lemmy.blahaj.zoneM
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        1 day ago

        My understanding was that it wouldn’t convert to T, but it will suppress its own effects and be less feminizing than a lower dose. This lines up with my experience where it felt like my progress stalled without reverting. E is much safer than T in that you can have much higher levels without causing serious complications, but you still want to be in a sweet spot.